In 2009, Palermo signed with the talent agency Wilhelmina International Inc. to focus full-time on development of her brand. She became a guest editor for the Gap’s now-defunct Piperlime. com in 2011 and appeared as a guest judge on Project Runway Season 9. In 2010, Palermo modeled for the Autumn/Winter campaigns by Mango and Hogan. In October 2011, Palermo launched her personal website, which consists of editorial content about fashion, beauty and lifestyle written by full-time writers and contributing editors. She also appeared as a guest judge on Britain and Ireland’s Next Top Model Season 7. Later in 2012, the New York Post named Palermo as the best dressed New Yorker of Page Six. Palermo appeared on the August 2018 cover of Glamour Mexico and has shot editorials for magazines, including Grazia Australia and ¡Hola! Fashion Magazine. She was also on the cover of Cosmopolitan, InStyle, Elle, Flare, Marie Claire, Arcadia, Lucky, Brides, Harper’s Bazaar, L’Officiel, Tatler and Stella.